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Nearly all cases of abnormal lactate accumulation involve at least one promoting factor beyond hypoxia, such as mitochondrial overload 28 or immune cell activation

SaA: Resources, Visualization, Formal Analysis, Investigation, Software, Writingreview and editing

however, our data show that BACH1 stabilization promotes angiogenesis, which may be attributed to cell type specificity or context-dependent downstream targets (e.g., PDGFR instead of HO-1) [17, 18]

J Integr Agric 20:12661276

Our results showed that throughout the hepatic I/R process, VNS significantly regulated the expression levels of various iconic factors and greatly enhanced the protein expression levels of nuclear factor erythroid 2-related factor 2 (Nrf2) and hemeoxygenase-1 (HO-1) in the kidneys