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Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

Front Physiol (2014) 5:516

Changes in body markers such as insulin response or lipid profiles may become measurable within 2-4 weeks

Psychiatry 89 GuoZ.LiuX.XuS.HouH.ChenX.ZhangZ.et al (2018)

Further proteomic analysis of the epididymis and sperm revealed that proteins essential in metabolism, ROS production, stress, inflammation and in the regulation of reproductive function were adversely affected (137)