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Description

Bailey, T

Butler IJ, O'Flynn ME, Seifert WE Jr, Howell RR

Hormonal regulation : Fat tissue produces leptin and other hormones that influence metabolic rate and energy expenditure

The data we currently have on cagrilintide alone come from a deeper follow-up analysis of a larger study called REDEFINE 1

In clinical trials, constipation rates with cagrilintide ranged from approximately 10% to 25% depending on the dose, compared to roughly 5% to 8% with placebo

Cagrilintide clinical trial results The phase 2 dose-finding trial enrolled participants with overweight or obesity and tested cagrilintide doses ranging from 0.3 mg to 4.5 mg administered subcutaneously once weekly