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A previous study supported this, showing that treatment of SLC1A5 -knockdown HNSCC cell lines with V-9302 led to marked inhibition of glutamine metabolism, thereby suppressing growth and proliferation both in vitro and in vivo 97

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ELISA The photoaging effect caused by ultraviolet irradiation was evaluated by using ELISA kits to detect the expression levels of SOD, CAT, GSH-Px, IL-1, IL-6, TNF-, ROS, and MDA in serum and dorsal skin tissue, as per the manufacturers instructions

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This specific chemical structure acts as a potent reducing agent, allowing it to act like a cellular sponge for highly reactive, unstable molecules known as free radicals or reactive oxygen species (ROS)

10.1016/j.toxlet.2013.10.038 5 BoulosJ