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Neong SF, Billington EO, Congly SE

The acute gout model and treatment in rats All procedures involving animals were conducted in strict compliance with the Animal Management Regulations set forth by the Ministry of Health of the Peoples Republic of China and adhered to the Southern Medical Universitys Guidelines for the Care and Use of Experimental Animals

For example, studies have found that MOTS-c can reduce fat accumulation in the liver and improve liver function in models of fatty liver disease

Bakaeen FG, Jaroszewski DE, Rice DC, Walsh GL, Vaporciyan AA, Swisher SG , Benjamin R, Blackmon S, Reardon MJ

Infect Immun (2010) 78(9):402232

allergens or environmental pollutants can also promote ROS production 12,14,16