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NDDs such as Alzheimers disease (AD), Parkinsons disease (PD), Huntingtons disease (HD), and amyotrophic lateral sclerosis (ALS) have all been associated with neuroinflammation, which further speeds up disease progression

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HxuCBA, SapA, and PE have been shown to confer resistance to AMP LL-37 and a homologue of human -defensin in a chinchilla model of acute OM (Mason et al., 2005