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IGF-1 LR3 remains a strictly experimental agent, and its use is banned in athletic competitions just like GH or steroids

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For all these subgroups the new options including radiofrequency ablation, cooled radiofrequency and cryoablation offer a ray of hope

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Combination therapies targeting RCD are being clinically validated, but their long-term effects on clonal evolution, immune homeostasis and metabolic reprogramming remain to be fully explored