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10.1186/s13287-018-0797-1 282 TehranzadehJ.TonJ

Commonly reported observations include: Reduced joint stiffness, particularly morning stiffness Improved range of motion in affected joints Decreased reliance on anti-inflammatory medications Better tolerance of physical activity and exercise These clinical observations are valuable but represent anecdotal evidence

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71 Therapeutic modulation of the autophagy-mitophagy axis in metabolic diseases Pharmacological interventions Several pharmacological agents already in clinical use exert metabolic benefits, at least in part, through activation of autophagy and mitophagy