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Conclusion We summarized the specific characteristics of a broad taxonomic range of alternative animal models suitable for elucidating processes involved in delayed and accelerated senescence in terms of life expectancy, pre-existing discoveries, and available data and resources

doi:10.1073/pnas.0607965104 Romano A, Serviddio G, Calcagnini S, Villani R, Giudetti AM, Cassano T, Gaetani S (2017) Linking lipid peroxidation and neuropsychiatric disorders: focus on 4-hydroxy-2-nonenal

This specific type of irritation is often the first step in a breakout

It binds copper(II) with high affinity (association constant in the range of 10 to the power of 16 per molar, placing it among the tighter biological copper chelators)