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These outcomes were reported alongside increased expression of -AR mRNA, suggesting a possible upregulation of adrenergic signaling components

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Another aspect of the invention pertains to the use of small molecule quinoline derived cations of Formula IA for muscular therapy, wherein: R 5 is H or NH 2 , R 6 is H or F R 7 is H or NH 2 , R 8 is H or methyl