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These antiapoptotic mechanisms constitute vulnerabilities and, consequently, targeting them with either BCL2 family inhibitors 24,25,34 or via suppression of cFLIP 26 kills senescent cells

Cotransfection of this Gal4-dependent luciferase reporter with an expression vector encoding Zfp423 at a high dose produced only a weak decrease (2-fold)

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This is crucial in ensuring the stability and longevity of the Semaglutide solution