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The autochthonous, or resident/indigenous bacteria can often be associated to the part of mucus layer that overlies the epithelium, they can be embedded in the intestinal folds, or anchored to cells through different mechanisms, including production of adhesion molecules, formation of biofilms and/or by modulating the immune response of the intestine, which can in turn influence the anchoring of the microbes to the intestinal cells (Zhang et al., 2023a)

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