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Patients should be aware that if they experience concerning symptoms whilst taking B12 supplements, they should discuss this with their GP and report suspected adverse reactions via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)

Its intended for adults seeking a portable option to align with their daily habits

Generally, it entails combining powdered peptide with a measure of bacteriostatic water to create a solution

The Phase 2b protocol used one dose per day for 12 weeks

and diurnal fluctuations in symptoms with worsening in the evening and at night

The Pernicious Anaemia Society notes this is well documented but poorly understood, and that some patients self-inject more frequently