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Ji J, Yang H

Sirtuin-1 activation controls tumor growth by impeding Th17 differentiation via STAT3 deacetylation

Yao T, Yao YY, Wang JZ, Jiang SM, Li LJ

Natural products target other pathways to induce iron death Currently, there are reports showing that there are other pathways and proteins that can affect cell death by ferroptosis

NADPH oxidases generate ROS as O 2 or H 2 O 2 depending on the isoform and contextNOX1/2/3 primarily release O 2 that dismutates to H 2 O 2 , NOX4 predominantly yields H 2 O 2 and Ca-activated NOX5 together with epithelial DUOX1/2 contribute directly to H 2 O 2 production at barrier surfaces (Kim and Moon 2024)