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L-Glutathione deficiency leads to increased oxidative stress, accumulation of toxins and heavy metals, reduced ability to detoxify the toxins and heavy metals from the body, skin issues, and aging, etc

Au NPs also decreased GEM resistance in cancer (420)

Appl Biochem Biotechnol 168:198205 Wang C, Zhang J, Wu H, Li Z, Ye Q (2015) Heterologous gshF gene expression in various vector systems in Escherichia coli for enhanced glutathione production

However, emerging data suggest that different PD therapies exert differential effects on gut microbiota, as shown in Table 4

10.3389/fbioe.2022.866195 [DOI] [PMC free article] [PubMed] [Google Scholar] Wang J., Zhu Q., Cao D., Peng Q., Zhang X., Li C., et al

Cancer Lett 239(2):271280 Huang W-H, Lee A-R, Yang C-H (2006) Antioxidative and anti-inflammatory activities of polyhydroxyflavonoids of Scutellaria baicalensis GEORGI