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Since all cellular and tissue-level effects ultimately originate from structural and functional alterations in molecular components, a comprehensive understanding of blue light-induced molecular damage is clearly warranted

Briefly, cell or tissue protein lysates were assayed in transparent 96-well plates (Greiner 655101) in the presence of 1 mM of the GGT substrate L-glutamic acid -p-nitroanilide (GpNA, Cayman 36209) and 20 mM of the transpeptidation acceptor glycyl-glycine (Sigma-Aldrich G1002) in Tris-HCl 100 mM pH 8

All drugs were administered by gavage after the TSCI surgery for at most 7 days

A review article by Bernard et al

The loss of NM also leads to a reduction in dorsolateral nigral hyperintensity in nigrosome 1 of the substania nigra on susceptibility-weighted images, often referred to as loss of the swallow-tail sign

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