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10.15698/cst2021.05.249 28 ChartierC.ElHawaryH.BaradaranA.VorstenboschJ.XuL.EfanovJ

10.3390/ijerph17239049 [PMC free article: PMC7731387] [PubMed: 33291649] [CrossRef] Kimura T, Kanasaki A, Hayashi N, Yamada T, Iida T, Nagata Y, et al

Proper storage and careful handling help maintain peptide integrity and ensure reliable experimental outcomes

GLP-1 has been demonstrated to induce natriuresis and diuresis, likely involving the inhibition of the sodiumhydrogen exchanger 3 (NHE3) localized at the brush border of the renal proximal tubular cells (192)

Lazarus Nature Reviews Gastroenterology & Hepatology .2024

Preclinical animal and in vitro studies are largely acute, yet chronic exposure better reflects real-world use 16 and may reveal mechanisms of fibrosis, tissue remodeling, and oxidative stress