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ASP, owing to its high solubility, biocompatibility, biodegradability, abundant hydroxyl groups, and modifiability, is an ideal candidate for constructing amphiphilic polymeric micelles with therapeutic potential (226, 227)

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Chronic exposure to ethanol can lead to decreased serotonin levels due to its effects on the synthesis and release of serotonin, primarily by influencing tryptophan metabolism

Mechanistically, mTORC1 promotes the proteasome-mediated destabilization of CREB2 to suppress SIRT4 (a mitochondria-localized member of the sirtuin family), which inhibits GDH, thereby enhancing GDH enzymatic activity

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Thromb Haemost (2016) 115(3):5919