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Specifically, germ-free mouse models or FMT can be adopted to confirm a causal chain that iron overload mediates a reduction of gut Lactobacillus , which in turn aggravates the development of OA

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Not all essential oils can be used internally

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it is unknown whether these conditions exacerbate CIN-related ferroptosis by pre-disrupting iron homeostasis or antioxidant capacity, which limits the development of risk-stratified therapies

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