glutathione thyroid nih Autoimmune Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors Frontiers | Selenium and thyroid

Goetsch, L

The results showed that irradiation aggravated arthritic severity, whereas ebselen treatment alleviated oxidative stress and inflammation in the synovium joints, increased collagen-II expression in the ankle joints, and finally improved the severity of arthritic clinical signs in the irradiated mice

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On the one hand, excess ROS accelerates the senescence and apoptosis of fibroblasts, endothelial cells, keratinocytes, and mesenchymal stem cells, thereby significantly hindering the development of granulation tissue, angiogenesis, and epithelial cell proliferation [89, 92]