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[30], a daily metformin dosage exceeding 2,000 mg was associated with a more pronounced decrease in vitamin B12 levels

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Individuals allergic to its ingredients should avoid it

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The limited human data includes a pilot study of IV infusion in 2 healthy adults (showing no adverse effects) 3 and an intra-articular injection study where 11 of 12 patients (91.6%) reported significant improvement in knee pain 4

This medication is commonly used to prevent nausea and vomiting