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Interestingly, reactivation of lipid peroxidation related to ferroptosis in macrophages improves bacterial clearance without causing significant macrophage death (Yu et al., 2025)

Lin SH, Zhang N, Godby J, Wang J, Marsh GD, Liao Z, Komaki R, Ho L, Hofstetter WL, Swisher SG , Mehran RJ, Buchholz TA, Elting LS, Giordano SH

A can self-aggregate, progressively creating oligomers and fibrils, which subsequently impair the function of glial cells and neurons, hence hastening the pathological advancement of AD [31]

CD13 is a therapeutic target in human liver cancer stem cells

Mitochondrial dysfunction also reshapes cellular metabolism in the inflamed gut

10.1016/j.imbio.2015.01.002 [DOI] [PubMed] [Google Scholar] 124.Zelante T, De Luca A, Bonifazi P, Montagnoli C, Bozza S, Moretti S, et al