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Journal of Experimental Botany

Surprisingly, glutathione depletion in mice extended lifespan, challenging assumptions

603 Meanwhile, EGCG downregulates dual oxidase and NOX expression while increasing SOD and GPX4 activities to reduce lipid peroxidation, suggesting that EGCG plays a neuroprotective role mainly by restoring iron homeostasis and redox balance in PD Drosophila

doi: 10.1016/j.arcmed.2018.04.007 248 ZhuCNChenGTianZQWangWZhongWQLiZet al

Since training and competition create more oxidative stress and damage, athletes have a higher need for antioxidants

In this case, as also stated by the authors, the supplementation could be efficacious only if it is going to be prophylactically used prior to an H5N1 influenza infection