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The results showed that the uptake of FITC-insulin by BMECs was inhibited when they had been preincubated with insulin, because the previous insulin competitively bound to the ectodomain of the IR

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447 In ischemia-reperfusion injury, high-density lipoprotein (HDL) inhibits BID-mediated mitochondrial apoptosis activation by regulating the expression and phosphorylation of the anti-apoptotic factor BCL-XL