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PD patients with mitochondrial dysfunction confirmed by pathologically especially in sporadic PD, against a backdrop of increased oxidative stress and elevated brain iron levels, this helps us to understand how mitochondrial abnormalities interconnected in PD pathogenesis (Mann et al., 1994

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FIGURE 8 Tocilizumab improved fever control and respiratory functioning in 21 severe COVID-19 patients in a Chinese clinical study (ChiCTR2000029765)

Regulated necrosis in pulmonary disease

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Often triggered by stress, processed diets, sedentary lifestyles, and environmental toxins, this silent burden can slowly wear down muscles, tissues, and even gut integrity