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Certain medications can interfere with B12 levels too

this occurs because there is not enough vitamin B12 in the diet, or poor absorption Pernicious anemiaa type of megaloblastic anemia caused by a lack of intrinsic factor, so that vitamin B12 is not absorbed Fatigue, weakness Nerve damage with numbness, tingling in the hands and legs Memory loss, confusion Dementia Depression Seizures Up to 15% of the general population has a B12 deficiency

The four subcutaneous areas that work best are the lower abdomen (away from the navel), the outer thigh, the back of the upper arm, and the flank or love-handle area