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Unlike Rac1 and Cdc42 that can be palmitoylated on their C-terminus to facilitate their recruitment to the lipid raft on the plasma membrane where gamma-secretase was located, RhoA was found mainly in the non-raft fraction (Kumanogoh et al., 2001

Astrocytes contribute to synapse elimination via type 2 inositol 1,4,5-trisphosphate receptor-dependent release of ATP

Mammalian target of rapamycin protein complex 2 regulates differentiation of th1 and th2 cell subsets via distinct signaling pathways

Liver Health: Assists the liver in metabolizing alcohol and other toxins

doi: 10.1080/00207450902782083 206 KowalczykP.KaczyskaK.KleczkowskaP.Bukowska-OkoI.KramkowskiK.SulejczakD

Ajani has received honoraria from Lilly, Bayer, Novartis, Five Prime Therapeutics, Taiho Pharmaceutical, Genentech, and Roche, received research funding from Novartis, Bristol-Myers Squibb, Taiho Pharmaceutical, Roche/Genentech, MedImmune, Amgen, Lilly/ImClone, Merck, Delta-Fly Pharma, Gilead Sciences, and Takeda, and received travel accommodation expenses (not for this work) from Novartis, Bayer, and Five Prime Therapeutics