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In cases of alcohol dependence, malnutrition, or suspected Vitamin B1 deficiency, the physician should consider appropriate thiamine supplementation, particularly prior to or concurrently with glucose infusion if indicated

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For more information, you may read the drug manufacturers instructions for use or watch this video

The Pulse Dosing Approach Instead of taking B12 every single day, some people do better taking larger amounts just 2-3 times per week

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If needed, B12 can be replaced with supplements or injections, under medical supervision