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Statistical method All data were analyzed using the SPSS software version 22.0, and the ShapiroWilk test was used to assess the normal distribution

According to the World Health Organization, about 5.7% of adults worldwide live with depression - thats roughly 332 million people, with women (6.9%) more often affected than men (4.6%)

doi: 10.1016/j.expneurol.2006.08.008

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doi: 10.1073/pnas.1821022116

This process gradually leads to the formation of oligomers and insoluble fibrils within the cytoplasm, ultimately accelerating the development of neurofibrillary tangles, a core pathological feature