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The significance of the mediation variable (M, representing either prefrontal or limbic CBF levels) was evaluated to determine its role in the causal pathway between the independent variable (X, prefrontal GABA levels) and dependent variable (Y, PTSD symptom severity)

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*Correspondence: Yasanandana Supunsiri Wijayasinghe, [email protected], Nitesh Kumar Poddar, [email protected], [email protected], Shahanavaj Khan, [email protected] These authors have contributed equally to this work ORCID: Yasanandana Supunsiri Wijayasinghe, Nitesh Kumar Poddar, This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers