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These effects may help enhance recovery and performance by protecting skeletal muscle tissue from damage caused by oxidative stress

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On the one hand, ferroptosis promotes osteoclast differentiation and inhibits Runx2-mediated osteoblast differentiation via the TfR1/ROS signaling axis, disrupting bone metabolic coupling and leading to subchondral bone instability, thereby exacerbating OA (Ru et al., 2023)

A standard curve was generated using standard H 2 O 2 (Carl Roth, Karlsruhe, Germany)

Mild joint discomfort or muscle stiffness linked to elevated IGF-1 levels

We found that in all four groups of mice Muribaculaceae (~40%) , Lachnsopiraceae NK4A136 (~25%), and Akkremansia (~25%) comprised 75% of the relative abundance of bacterial taxa across all groups ( Fig.2 )