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[PubMed: 15161945] (Among 107 patients with atrial fibrillation or flutter treated with dofetilide in clinical practice, none developed torsades de pointes although 26% had excessive QTc prolongation, and rates of conversion to and maintenance of normal sinus rhythm were similar or higher than reported in registration trials

Benefits: Improves circadian rhythm by promoting the delta rhythm, achieved in Stage 4 of sleep (the stage when Growth Hormone is made) Antioxidant effect in the brain via increases in glutathione peroxidase and superoxide dismutase Increased alertness, improved stress tolerance, and coping behavior during awake cycles Restoration of slow-wave sleep in Cushings Syndrome Possible anticonvulsant action by increasing the threshold to NMDA- and picrotoxin-induced convulsions Increase in testosterone levels when treating with DSIP alone (100-200 point increases have been observed) Side Effects: Potential to disrupt sleep

M.KundertJ

Vitamin C (1%): Vitamin C is a potent antioxidant that helps even out skin tone and brighten the complexion

NIH Public Access 24 (1), 7379

The formation of NFT in an aerobic intracellular environment raises the question of its stability and its interaction with biological molecules such as the omnipresent glutathione