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Therapeutic effects in hypoxic osteosarcoma cells The biological activities of NP4 were studied against human osteosarcoma (143B) and mouse osteosarcoma (K7M2) cells with different O 2 concentrations

A population-level study in India found curcumin intake up to 100 mg/day safe and associated with reduced cancer prevalence (Jutooru et al., 2010) FAO/WHO Joint Expert Committee on Food Additives (JECFA) considers 4 to 10 g of turmeric daily safe for healthy adults (Kocaadam and Sanlier, 2017)

Free Radic Biol Med 48(3):391398 Moon KH et al (2008) Mechanism of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated mitochondrial dysfunction in rat liver