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Gertz EW, Wisneski JA, Stanley WC, Neese RA

For example, miR-29a-3p is downregulated in PCOS

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Copper has a complex role in oxidative biology participating in both prooxidant chemistry (where free or weakly bound copper can catalyze damaging reactive-oxygen-species generation) and antioxidant chemistry (as the cofactor of Cu/Zn superoxide dismutase)

Cysteine deprivation can also induce ferroptosis, but this effect is mitigated by the transsulfuration pathway 10,11