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Direct in vitro comparisons of these mAbs showed comparable antibody-dependent cell-mediated toxicity (ADCC) and binding affinities, but remarkable differences in the ability to induce direct apoptosis, to induce complement-mediated cytotoxicity (CDC), and to induce antibody-dependent cell-mediated phagocytosis (ADCP)

doi: 10.1016/S1474-4422(21)00465-8, 3

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Notably, these metabolic changes were not influenced by metabolic syndrome, BMI, sex, or age, suggesting that they are indicative of fundamental pathophysiological processes rather than metabolic comorbidities [235, 236]

Penile Pain Advise patients that the most frequently occurring side-effect is penile pain after injection and is usually mild to moderate in severity [see Adverse Reactions (6.1)]