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STORAGE Lyophilized -20 C 24 months Reconstituted 2-8 C, 28 days PEER-REVIEWED EVIDENCE Lau DCW, et al

Never inject into the exact same spot within 12 weeks

527,528 Second-line medications Opioids and atypical opioids Tapentadol: A centrally acting analgesic with both opioid agonist and norepinephrine reuptake inhibition properties

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PMID 8626496