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The mRNA levels of GCLC and GS were both lower (50% and 30%, respectively) while mRNA levels of GCLM were unchanged

The results demonstrated that these nanocarriers possess characteristics enabling them to access the brain, and they are at least as effective as the corresponding free drugs in protecting against rotenone-induced reduction in cell viability, increased iron content, and oxidative stress

219 Together with its upstream regulators and downstream effectors, mTORC1 plays a significant role in regulating mitochondrial fission and fusion (Fig