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Implications for Alzheimers disease pathology

El pronstico es malo, con supervivencia del 20-30% a los 5 aos del diagnstico

Understanding the molecular and cellular mechanisms underlying the loss or gain of disorder-related detrimental effects mediated by astrocytes in different contexts has the potential to identify new treatment strategies for a wide variety of CNS disorders

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One successful example is the work of the Reymond group, who have utilized this approach to discover and optimize bicyclic peptidesa class of molecules with high stability due to their constrained structure

Plant Cell Physiol 34:12591266 Kaminaka H, Morita S, Nakajima M, Masmura T, Tanaka K (1998) Gene cloning and expression of cytosolic glutathione reductase in rice ( Oryza sativa L.)