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4.4 Other ferroptosis inhibitors Some small molecule inhibitors target pathways intersecting with ferroptosis regulation by modulating specific mechanisms (Table 1)

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Specifically, DDR2 interacted with Src kinase, leading to the nuclear translocation of homologous transcriptional regulators (yes-associated protein 1 [YAP1] and WW domain containing transcription regulator 1 [WWTR1]) of the Hippo pathway, which altered the expression level of ferroptosis-related genes

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Dormant NADPH oxidase contains two subunits: glycoprotein (gp)91phox (for phagocyte oxidase) and p22phox [63]

Resnick, M