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Using the miRDB custom prediction tool [7], we retrieved murine miRNAs that can potentially target the aforementioned human genes commonly expressed in transgenic mice to model human disease

The structure of ORF8 shows that it can form a dimer, and each promoter of ORF8 contains eight antiparallel -strands tied by three disulfide bonds

Xu S, Cherok E, Das S, Li S, Roelofs BA, Ge SX, et al

To test this hypothesis, we examined SLC7A11 expression levels from an RNA-Seq dataset with 16 CTCs and 12 available primary breast tumor samples from matched patients 29

Although testing in orthotopic models of GBM suggested effectiveness [58], promising results in GBM AGILE were not achieved and paxalisib will not move forward to stage 2 in that trial

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