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High dose oral cobalamin would be a reasonable alternative as maintenance in patients unable to tolerate intramuscular injections provided there is good compliance with treatment

What is missing There is no published human pharmacokinetic study of subcutaneous AOD-9604, no published human topical or intranasal exposure data, no Phase 3 efficacy trial, no long-term safety data beyond 24 weeks, and no published human cartilage or joint outcome data

And in skincare, the focus is not on applying NAD+ directly, but on using precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) to help support the skins natural NAD+ levels

We will perform a detailed history, exam, review and order any necessary imaging then identify the treatment approach that is appropriate for your specific condition

This information is for educational purposes only and is not a substitute for medical advice