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A novel model of continuous depletion of glutathione in mice treated with L-buthionine (S,R)-sulfoximine

Initial fatigue: Some report tiredness during first weeks

doi: 10.1016/j.steroids.2019.108496 91 SarkarDKChaturvediKOomizuSBoyadjievaNIChenCP

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In the cortex, tau is observed first in the medial temporal lobe and then, progresses to association cortices, consistent with Braak staging [313, 314]