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Pascual B, Prieto E, Arbizu J, Marti-Climent JM, Peuelas I, Quincoces G, et al

Studies on the linkage between Nrf2 and autophagy have shown that Nrf2 activates IKK and subsequent NF-B by enhancing the expression of p62, which explains NF-B-dependent autophagy activation (135137)

Furthermore, PPAR- agonists may regulate the energy metabolism of SGECs by upregulating adiponectin, suggesting a multifaceted role for PPAR- in managing SS [178]

J Exp Bot 71:37353748

Vitamin B6 also helps produce neurotransmitters (like GABA, dopamine, serotonin) that influence mood and cognitive function, and regulates the immune response by helping inhibit proinflammatory cytokines

doi: 10.1093/plankt/fbab091