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SCF FBXO22 -Degrader-NSD2 PWWP1 ternary complex formation for cryo-EM Formation of the SCF FBXO22 -UNC10088-NSD2 PWWP1 and SCF FBXO22 -UNC10415667-NSD2 PWWP1 ternary complexes was performed by incubating SKP1-FBXO22, CUL1-RBX1, NSD2 PWWP1, and UNC10088 or UNC10415667 at a 1:1:1:1 molar ratio for 4 h on ice

HDL3 stimulates multiple signaling pathways in human skin fibroblasts

This dual-responsiveness can enhance therapeutic precision, but it also introduces challenges in terms of premature degradation and chemical instability during formulation or circulation

The external computer that is running the server program is referred to as the FTP server

Holtman IR, Raj DD, Miller JA, Schaafsma W, Yin Z, et al

The sciatic nerve invasion model was used to evaluate the crosstalk between cancer cells and nerves in vivo