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As we know, Ferroptosis is regulated mainly by the GSHGPX4 pathway 49 , and we experimentally demonstrated that TNF- inhibits EBV reactivation by affecting the classical pathway of ferroptosis

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Such reactions are commonly accomplished by protecting sensitive functional groups on the rest of the molecule whilst generating an anion on one or both of the nitrogen by adding a strong base such as sodium amide, LDA, a Grignard reagent, or LiN(i-Pr) 2