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The GSH depletion which was observed in the present study [Table/Fig-1] can be caused by acetaldehyde accumulation [32], and increased utilization by the glutathione-S-transferases as well as GGT, the enzymes which are involved in the detoxification of xenobiotics

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By understanding the mechanism on how GSH levels are altered by disease, xenobiotic exposure, and environmental factors the variance between the innate ( i.e

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[DOI] [PubMed] [Google Scholar] Merksamer PI, Liu Y, He W, Hirschey MD, Chen D, Verdin E

Targeting glutamate metabolism holds immense potential for enhancing anti-tumor immunity, presenting novel avenues for therapeutic intervention