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The viability of senescent glioblastoma cells decreased by over 60% following a two-day treatment with ABT-737 (2.5 M), whereas the viability reduction did not exceed 15% for proliferating cells [106]

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Senescent cells can secrete soluble inflammatory cytokines, growth factors, interleukins, chemokines, degradative enzymes such as matrix metalloproteinase, and insoluble extracellular matrix components

Co also serves as a cofactor in some non-corrin enzymes

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