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Glucose can be catabolized to lactate during glycolysis or glucose-derived carbons can enter the tricarboxylic acid cycle (TCA)

Reciprocally, cells that were severely depleted of GSH preserved thioredoxin in their wildtype redox state, without any protein compensatory increase, indicating that the thioredoxin pathway could entirely assume the thiolredox maintenance duties of the cell

Y., Banuelos, J., Corts, M

Neurology 78 , 13231329 (2012)

The findings also could have implications for future interventions that raise ApoM in patients with heart failure

J Comp Neurol 505:158165 Rosado JO, Salvador M, Bonatto D (2007) Importance of the trans-sulfuration pathway in cancer prevention and promotion