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doi: 10.1126/science.1078540

This encompasses mood, wakefulness and sleep, appetite, aggression frequency, circadian rhythms, body temperature, and neuroendocrine activity

doi:10.1016/S0893-133X(97)00181-4

Yes, but always do a patch test first

Thus, we consider that together with other clinical variables and biomarkers, global MFIS and its domains constitute a diagnostic and prognostic aid in clinical practice for the design of personalized therapeutic strategies