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doi:10.1016/j.bj.2018.10.009

14 :e22705 82

[1] [2] These typically diminish over time as the body adjusts to the medication

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Clinical picture Several signs characterize the clinical picture of DSDs and are all included among the following criteria used for raising the clinical suspicion of these conditions according to patients age (Table 3)

Electrophysiology To examine the acute effects of GH on the membrane excitability of AgRP neurons, whole-cell patch-clamp recordings were performed in hypothalamic slices of male AgRP-reporter mouse (812 weeks old)